IL33 (NM_033439) Human Recombinant Protein

SKU TP723790

Purified recombinant protein of Human interleukin 33 (IL33), transcript variant 1

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human IL-33, the region of Ser112-Thr270, from gene Accession# NM_ 033439
• Tag: Tag Free
• Predicted MW: 18 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: Human IL-33 induces the proliferation of mouse D10.G4.1 cells in a dose-dependent manner. The ED50 for this effect is 0.1 to 0.5 ng/mL.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_254274
• Locus ID: 90865
• UniProt ID: O95760
• Cytogenetics: 9p24.1
• RefSeq Size: 2718
• RefSeq ORF: 810
• Synonyms: C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV
• Summary: The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
• Protein Families: Secreted Protein
• Protein Pathways: Cytosolic DNA-sensing pathway