IL17F (NM_052872) Human Recombinant Protein

SKU TP723712

Purified recombinant protein of Human interleukin 17F (IL17F)

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human IL-17F, the region of Arg31-Gln163, from gene Accession# NM_052872
• Tag: Tag Free
• Predicted MW: 14.9 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: The ED50 is 400 - 800 ng/ml, corresponding to a specific activity of 2.5 ??1.25 x 10^3 units/mg, determined by the dose dependent stimulation of CXCL1 production in human fibroblast.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_443104
• Locus ID: 112744
• UniProt ID: Q96PD4
• Cytogenetics: 6p12.2
• RefSeq Size: 808
• RefSeq ORF: 489
• Synonyms: CANDF6; IL-17F; ML-1; ML1
• Summary: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Secreted Protein