IGFBP2 (NM_000597) Human Recombinant Protein

CAT#: TP723170

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Purified recombinant protein of Human insulin-like growth factor binding protein 2, 36kDa (IGFBP2).


Product Datasheet for 'TP723170'


  View other "IGFBP2" proteins (4)

USD 240.00


Availability*
5 Days

Size
    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Human insulin-like growth factor binding protein 2, 36kDa (IGFBP2).
Species Human
Expression Host Hi-5 insect
Expression cDNA Clone or AA Sequence EVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACQVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ
Tag Tag Free
Predicted MW 31.5 kDa
Concentration Resuspend the protein in the desired concentration in proper buffer
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Bioactivity Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_000588
Locus ID 3485
Refseq Size 1439
Cytogenetics 2q35
Refseq ORF 984
Synonyms IBP2; IGF-BP53
Summary The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein

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Other Versions

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