TPSB2 (NM_024164) Human Recombinant Protein

SKU
TP721034
Purified recombinant protein of Human tryptase beta 2 (gene/pseudogene) (TPSB2)
  $340.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Ala19-Pro275
Tag C-His
Predicted MW 29.64 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_077078
Locus ID 64499
UniProt ID P20231
Cytogenetics 16p13.3
RefSeq Size 1165
RefSeq ORF 825
Synonyms TPS2; tryptaseB; tryptaseC
Summary Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Peptidases, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "TPSB2" proteins (3)
SKU Description Size Price
LC402980 Lyophilized TPSB2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402980 Transient overexpression lysate of tryptase beta 2 (gene/pseudogene) (TPSB2) (as WB positive control) 100 ug
$436.00
TP761849 Purified recombinant protein of Human tryptase beta 2 (gene/pseudogene) (TPSB2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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