Osteopontin (SPP1) (NM_000582) Human Recombinant Protein

CAT#: TP720449

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Recombinant protein of human secreted phosphoprotein 1 (SPP1), transcript variant 2

  View other "SPP1" proteins (14)

USD 300.00

2 Weeks

    • 10 ug

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Product Data
Description Recombinant protein of human secreted phosphoprotein 1 (SPP1), transcript variant 2
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC205118, encoding the secreted form (Ile17-Asn314) of human SPP1
Tag N-His
Predicted MW 34.7 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_000573
Locus ID 6696
Refseq Size 1616
Cytogenetics 4q22.1
Refseq ORF 900
Synonyms BNSP; BSPI; ETA-1; OPN
Summary The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway


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