PTPRN (NM_002846) Human Recombinant Protein

CAT#: TP710233

Purified recombinant protein of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9 insect cells

  View other "PTPRN" proteins (6)

USD 515.00

In Stock*

    • 20 ug

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Frequently bought together (1)
Rabbit Polyclonal Anti-PTPRN Antibody
    • 100 ul

USD 380.00

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Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC220230, encoding human full-length PTPRN
Predicted MW 103 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002837
Locus ID 5798
UniProt ID Q16849, Q96IA0
Cytogenetics 2q35
Refseq Size 3649
Refseq ORF 2937
Synonyms IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Type I diabetes mellitus


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