PTPRN (NM_002846) Human Recombinant Protein
SKU
TP710233
Purified recombinant protein of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9 insect cells
$515.00
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Product Data | |
Species | Human |
---|---|
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
Protein Sequence
A DNA sequence from TrueORF clone, [RC220230], encoding human full-length PTPRN
|
Tag | C-DDK |
Predicted MW | 103 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002837 |
Locus ID | 5798 |
UniProt ID | Q16849 |
Cytogenetics | 2q35 |
RefSeq Size | 3649 |
RefSeq ORF | 2937 |
Synonyms | IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N |
Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Type I diabetes mellitus |
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FAQs |
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Recombinant Protein Resources |
SKU | Description | Size | Price | |
---|---|---|---|---|
LC419074 | PTPRN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
LY419074 | Transient overexpression lysate of protein tyrosine phosphatase, receptor type, N (PTPRN) | 100 ug |
$665.00
|
|
TP710234 | Purified recombinant protein of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1, residues 35-575aa, with C-terminal DDK tag, expressed in sf9 insect cells | 20 ug |
$515.00
|
|
TP721209 | Purified recombinant protein of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1 | 10 ug |
$330.00
|
|
TP721211 | Purified recombinant protein of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1 | 10 ug |
$330.00
|
|
TP721213 | Purified recombinant protein of Human protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 1 | 10 ug |
$330.00
|
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.