Von Willebrand Factor (VWF) (NM_000552) Human Recombinant Protein

SKU TP710179

Recombinant protein of human von Willebrand factor (VWF), residues 764-1263aa, with C-terminal DDK tag, expressed in sf9, 20ug

Product Data

• Species: Human
• Expression Host: Sf9
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, [RC218497], encoding the region(Met-Ser764-Ser1263) of Homo sapiens VWF
• Tag: C-DDK
• Predicted MW: 55 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_000543
• Locus ID: 7450
• UniProt ID: P04275
• Cytogenetics: 12p13.31
• RefSeq Size: 8833
• RefSeq ORF: 8439
• Synonyms: F8VWF; VWD
• Summary: This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades, ECM-receptor interaction, Focal adhesion