PTCH1(PTCH1) (NM_000264) Human Recombinant Protein

CAT#: TP710156

Recombinant protein of human patched homolog 1 (Drosophila) (PTCH1), transcript variant 1b, residues 770-1027, with C-terminal DDK tag, expressed in sf9, 20ug

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 Product Datasheet for 'TP710156'

USD 399.00


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    • 20 ug

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Product Data
Description Recombinant protein of human patched homolog 1 (Drosophila) (PTCH1), transcript variant 1b, residues 770-1027, with C-terminal DDK tag, expressed in sf9, 20ug
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC216999, encoding the region(Met-Arg770-Trp1027) of Homo sapiens PTCH1
Tag C-DDK
Predicted MW 30.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_000255
Locus ID 5727
Refseq Size 6825
Cytogenetics 9q22.32
Refseq ORF 4341
Synonyms BCNS; HPE7; NBCCS; PTC; PTC1; PTCH; PTCH11
Summary This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008].
Protein Families
Protein Pathways
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