MTOR (NM_004958) Human Recombinant Protein

CAT#: TP320457

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Recombinant protein of human FK506 binding protein 12-rapamycin associated protein 1 (FRAP1/MTOR)


 Product Datasheet for 'TP320457'

 Cited in 5 publications.

  View other "MTOR" proteins (4)

USD 788.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human FK506 binding protein 12-rapamycin associated protein 1 (FRAP1/MTOR)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 288.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
Locus ID 2475
Refseq Size 8680
Cytogenetics 1p36.22
Refseq ORF 7647
Synonyms FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS
Summary The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adipocytokine signaling pathway, ErbB signaling pathway, Glioma, Insulin signaling pathway, mTOR signaling pathway, Pathways in cancer, Prostate cancer, Type II diabetes mellitus

Citations (5)

Documents

Other Versions

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