MTOR (NM_004958) Human Recombinant Protein

CAT#: TP320457

Recombinant protein of human FK506 binding protein 12-rapamycin associated protein 1 (FRAP1/MTOR)

 Product Datasheet for 'TP320457'

 Cited in 4 publications.

  View other "MTOR" proteins (4)

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USD 788.00

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    • 20 ug

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Product Data
Description Recombinant protein of human FK506 binding protein 12-rapamycin associated protein 1 (FRAP1/MTOR)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence RC220457
Predicted MW 288.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
Locus ID 2475
Refseq Size 8680
Cytogenetics 1p36.22
Refseq ORF 7647
Summary The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008].
Protein Families Protein Kinase, Druggable Genome
Protein Pathways ErbB signaling pathway, mTOR signaling pathway, Insulin signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Pathways in cancer, Glioma, Prostate cancer, Acute myeloid leukemia

Citations (4)


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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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