DHODH (NM_001361) Human Recombinant Protein

CAT#: TP309034

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Recombinant protein of human dihydroorotate dehydrogenase (DHODH), nuclear gene encoding mitochondrial protein


 Product Datasheet for 'TP309034'

 Cited in 2 publications.

  View other "DHODH" proteins (5)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human dihydroorotate dehydrogenase (DHODH), nuclear gene encoding mitochondrial protein
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 41.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Enzyme activity (PMID: 27641501)
Enzyme activity (PMID: 28196676)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001352
Locus ID 1723
Refseq Size 2438
Cytogenetics 16q22.2
Refseq ORF 1185
Synonyms DHOdehase; POADS; URA1
Summary The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Metabolic pathways, Pyrimidine metabolism

Citations (2)

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Other Versions

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