MAVS (NM_020746) Human Recombinant Protein

CAT#: TP308175

Recombinant protein of human virus-induced signaling adapter (VISA), nuclear gene encoding mitochondrial protein

Product images

Specifications

Product Data

• Description: Recombinant protein of human virus-induced signaling adapter (VISA), nuclear gene encoding mitochondrial protein
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 56.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Bioactivity: Surface Plasmon Ressonance (SPR) (PMID: 27252539)
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_065797
• Locus ID: 57506
• Refseq Size: 11771
• Cytogenetics: 20p13
• Refseq ORF: 1620
• Synonyms: CARDIF; IPS-1; IPS1; VISA
• Summary: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
• Protein Families: Transmembrane
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway