MAVS (NM_020746) Human Recombinant Protein

CAT#: TP308175

Recombinant protein of human virus-induced signaling adapter (VISA), nuclear gene encoding mitochondrial protein

Product images

Coomassie blue staining of purified MAVS protein (Cat# TP308175). The protein was produced from HEK293T cells transfected with MAVS cDNA clone (Cat# RC208175) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Description: Recombinant protein of human virus-induced signaling adapter (VISA), nuclear gene encoding mitochondrial protein
• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence: Recombinant protein was produced with TrueORF clone, RC208175. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 56.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Bioactivity: Surface Plasmon Ressonance (SPR) (PMID: 27252539)
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_065797
• Locus ID: 57506
• Refseq Size: 11771
• Cytogenetics: 20p13
• Refseq ORF: 1620
• Synonyms: CARDIF; IPS-1; IPS1; VISA
• Summary: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
• Protein Families: Transmembrane
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway