MAVS (NM_020746) Human Recombinant Protein
Recombinant protein of human virus-induced signaling adapter (VISA), nuclear gene encoding mitochondrial protein
Product Datasheet for 'TP308175'
Specifications
Product Data | |
Description | Recombinant protein of human virus-induced signaling adapter (VISA), nuclear gene encoding mitochondrial protein |
Species | Human |
Expression Host | HEK293T |
Tag | C-Myc/DDK |
Predicted MW | 56.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Bioactivity | Surface Plasmon Ressonance (SPR) (PMID: 27252539) |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Reference Data | |
RefSeq | NP_065797 |
Locus ID | 57506 |
Refseq Size | 11771 |
Cytogenetics | 20p13 |
Refseq ORF | 1620 |
Synonyms | CARDIF; IPS-1; IPS1; VISA |
Summary | This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Protein Families | Transmembrane |
Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway |
Citations (2)
The use of this Proteins has been cited in the following citations: |
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Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains
,Hu, Y;Dong, X;He, Z;Wu, Y;Zhang, S;Lin, J;Yang, Y;Chen, J;An, S;Yin, Y;Shen, Z;Zeng, G;Tian, H;Cai, J;Yang, Y;Guan, H;Wu, J;Li, M;Zhu, X;,
Cell Biosci 2019
,PubMed ID 31183075
[MAVS]
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Dengue virus subverts host innate immunity by targeting adaptor protein MAVS
,He, Z;Zhu, X;Wen, W;Yuan, J;Hu, Y;Chen, J;An, S;Dong, X;Lin, C;Yu, J;Wu, J;Yang, Y;Cai, J;Li, J;Li, M;,
J. Virol. Jun 2016
,PubMed ID 27252539
[MAVS]
|
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
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LC412370 | MAVS HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
LY412370 | Transient overexpression lysate of mitochondrial antiviral signaling protein (MAVS), nuclear gene encoding mitochondrial protein |
USD 315.00 |
|
PH308175 | MAVS MS Standard C13 and N15-labeled recombinant protein (NP_065797) |
USD 1,995.00 |
|
AR50771PU-N | Recombinant human MAVS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 820.00 |
|
AR50771PU-S | Recombinant human MAVS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 320.00 |
USD 299.00
USD 335.00