PNMT (NM_002686) Human Recombinant Protein

CAT#: TP306586

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Recombinant protein of human phenylethanolamine N-methyltransferase (PNMT)


 Product Datasheet for 'TP306586'

  View other "PNMT" proteins (5)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human phenylethanolamine N-methyltransferase (PNMT)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 30.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002677
Locus ID 5409
Refseq Size 958
Cytogenetics 17q12
Refseq ORF 846
Synonyms PENT; PNMTase
Summary The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Tyrosine metabolism

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