EXOSC1 (NM_016046) Human Recombinant Protein

CAT#: TP306007

Recombinant protein of human exosome component 1 (EXOSC1)

Product images

Coomassie blue staining of purified EXOSC1 protein (Cat# TP306007). The protein was produced from HEK293T cells transfected with EXOSC1 cDNA clone (Cat# RC206007) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Description: Recombinant protein of human exosome component 1 (EXOSC1)
• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence: Recombinant protein was produced with TrueORF clone, RC206007. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 21.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_057130
• Locus ID: 51013
• Refseq Size: 1150
• Cytogenetics: 10q24.1
• Refseq ORF: 585
• Synonyms: CGI-108; CSL4; Csl4p; p13; SKI4; Ski4p
• Summary: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
• Protein Pathways: RNA degradation