XRCC1 (NM_006297) Human Recombinant Protein

CAT#: TP304952

Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)

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 Product Datasheet for 'TP304952'

USD 680


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Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC204952. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 69.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_006288
Locus ID 7515
Refseq Size 2083
Cytogenetics 19q13.31
Refseq ORF 1899
Synonyms RCC; RCC
Summary The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
Protein Families
Protein Pathways
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