Acetyl CoA synthetase(ACSS2) (NM_018677) Human Recombinant Protein

Specifications

Product Data
Description	Recombinant protein of human acyl-CoA synthetase short-chain family member 2 (ACSS2), transcript variant 1
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Recombinant protein was produced with TrueORF clone, RC204260. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag	C-MYC/DDK
Predicted MW	78.4 kDa
Concentration	>50 ug/mL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq	NP_061147
Locus ID	55902
Refseq Size	2925
Cytogenetics	20q11.22
Refseq ORF	2103
Synonyms	ACAS2; ACECS; ACS; ACSA; dJ1161H23.1
Summary	This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009].
Protein Pathways	Glycolysis / Gluconeogenesis, Pyruvate metabolism, Propanoate metabolism, Metabolic pathways

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