hemoglobin subunit gamma 1 (HBG1) (NM_000559) Human Recombinant Protein

CAT#: TP303084

Recombinant protein of human hemoglobin, gamma A (HBG1), 20 µg

Size: 20 ug 100 ug 1 mg


  View other "hemoglobin subunit gamma 1" proteins (3)

USD 867.00

In Stock*

Size
    • 20 ug

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Frequently bought together (2)
HBG1 Rabbit polyclonal Antibody
    • 100 ul

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Other products for "hemoglobin subunit gamma 1"

Specifications

Product Data
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence
>RC203084 protein sequence
Red=Cloning site Green=Tags(s)

MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLT
SLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVAS
ALSSRYH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 15.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000550
Locus ID 3047
UniProt ID P69891, D9YZU8
Cytogenetics 11p15.4
Refseq Size 584
Refseq ORF 441
Synonyms HBG-T2; HBGA; HBGR; HSGGL1; PRO2979
Summary The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

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