Elafin / PI3 (23-117, His-tag) Human Protein

SKU AR51935PU-N

Elafin / PI3 (23-117, His-tag) human recombinant protein, 0.25 mg

Product Data

• Species: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  AVTGVPVKGQ DTVKGRVPFN GQDPVKGQVS VKGQDKVKAQ EPVKGPVSTK PGSCPIILIR CAMLNPPNRC LKDTDCPGIK KCCEGSCGMA CFVPQHHHHH H
• Tag: His-tag
• Predicted MW: 10.7 kDa
• Concentration: lot specific
• Purity: >85% by SDS - PAGE.
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified protein; Buffer System: Phosphate buffered saline (pH 7.4), 10% glycerol
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Preparation: Liquid purified protein
• Protein Description: Recombinant human PI3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_002629
• Locus ID: 5266
• UniProt ID: P19957
• Cytogenetics: 20q13.12
• Synonyms: Elastase-specific inhibitor, ESI, Peptidase inhibitor 3, PI-3, SKALP, WAP3, WFDC14
• Summary: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]
• Protein Families: Secreted Protein, Transmembrane