Interleukin-2 / IL2 (21-169, His-tag) Human Protein

SKU AR51807PU-S

Interleukin-2 / IL2 (21-169, His-tag) human recombinant protein, 50 µg

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLK LPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFE CQFDDESATV VDFLRRWIAF SQSIISTSPQ
• Tag: His-tag
• Predicted MW: 17.3 kDa
• Concentration: lot specific
• Purity: >90% by SDS - PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified protein; Buffer System: Phosphate Buffered Saline (pH 7.4)
• Bioactivity: Specific: Measured in a cell proliferation assay using CTLL-2 mouse T lymphocyte. The ED50 for this effect is < 0.9 ng/ml.
• Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
• Preparation: Liquid purified protein
• Protein Description: Recombinant mouse IL2 was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_032392
• Locus ID: 16183
• UniProt ID: P04351
• Cytogenetics: 3 18.3 cM
• Synonyms: IL-2, TCGF
• Summary: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.[UniProtKB/Swiss-Prot Function]