Interleukin-9 / IL9 (1-144, His-tag) Human Protein

SKU AR51785PU-S

Interleukin-9 / IL9 (1-144, His-tag) human recombinant protein, 50 µg

Product Data

• Species: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MLLAMVLTSA LLLCSVAGQG CPTLAGILDI NFLINKMQED PASKCHCSAN VTSCLCLGIP SDNCTRPCFS ERLSQMTNTT MQTRYPLIFS RVKKSVEVLK NNKCPYFSCE QPCNQTTAGN ALTFLKSLLE IFQKEKMRGM RGKIHHHHHH Red : Signal peptide
• Tag: His-tag
• Predicted MW: 14.5 kDa
• Concentration: lot specific
• Purity: >85% by SDS – PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified protein; Buffer System: Phosphate buffer saline (pH 7.4) containing 10% glycerol.
• Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
• Preparation: Liquid purified protein
• Protein Description: Recombinant human IL9, fused to His-tag at C-terminus, was expressed in Sf9 and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_000581
• Locus ID: 3578
• UniProt ID: P15248
• Cytogenetics: 5q31.1
• Synonyms: IL-9, T-cell growth factor P40, P40 cytokine
• Summary: The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Asthma, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway