NRK1 / C9orf95 (1-199, His-tag) Human Protein
$1,005.00
3 Weeks*
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Product Data | |
Species | Human |
---|---|
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MGSMKTFIIG ISGVTNSGKT TLAKNLQKHL PNCSVISQDD FFKPESEIET DKNGFLQYDV LEALNMEKMM SAISCWMESA RHSVVSTDQE SAEEIPILII EGFLLFNYKP LDTIWNRSYF LTIPYEECKR RRSTRVYQPP DSPGYFDGHV WPMYLKYRQE MQDITWEVVY LDGTKSEEDL FLQVYEDLIQ ELAKQKCLQV TA
|
Tag | His-tag |
Predicted MW | 25.6 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Presentation State | Purified |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 2 mM DTT, 200 mM NaCl |
Preparation | Liquid purified protein |
Protein Description | Recombinant human NRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Reference Data | |
RefSeq | NP_001121075 |
Locus ID | 54981 |
UniProt ID | Q9NWW6 |
Cytogenetics | 9q21.13 |
Synonyms | Nicotinamide riboside kinase 1, NmR-K1, RNK1 |
Summary | Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]).[supplied by OMIM, Mar 2008] |
Protein Pathways | Nicotinate and nicotinamide metabolism |
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