Prolactin / PRL (recombinant) Human Protein
$1,005.00
3 Weeks*
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Product Data | |
Species | Human |
---|---|
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Protein Sequence
MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC
|
Predicted MW | 23 kDa |
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Presentation State | Purified |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate buffer saline (pH 7.4) |
Bioactivity | Biological: Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 for this effect is less or equal to 0.5 ng/ml. |
Endotoxin | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Preparation | Liquid purified protein |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Reference Data | |
RefSeq | NP_000939 |
Locus ID | 5617 |
UniProt ID | P01236 |
Cytogenetics | 6p22.3 |
Synonyms | GHA1 |
Summary | This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.