NAP2 / PPBP / CXCL7 (35-128) Human Protein

SKU AR39049PU-L

NAP2 / PPBP / CXCL7 (35-128) human recombinant protein, 0.5 mg

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MSSTKGQTKR NLAKGKEESL DSDLYAELRC MCIKTTSGIH PKNIQSLEVI GKGTHCNQVE VIATLKDGRK ICLDPDAPRI KKIVQKKLAG DESAD
• Predicted MW: 10.3 kDa
• Concentration: lot specific
• Purity: >90%
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified peptide; Buffer System: 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol, 1 mM DTT
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method )
• Preparation: Liquid purified peptide
• Protein Description: Recombinant human PPBP protein was expressed in E.coli and purified by using conventional chromatograph.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_002695
• Locus ID: 5473
• UniProt ID: P02775
• Cytogenetics: 4q13.3
• Synonyms: CTAP3, SCYB7, TGB1, THBGB1
• Summary: The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction