Synaptotagmin-1 (136-382, His-tag) Human Protein

SKU AR39031PU-S

Synaptotagmin-1 (136-382, His-tag) human recombinant protein, 10 µg

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MEPKEEEKLG KLQYSLDYDF QNNQLLVGII QAAELPALDM GGTSDPYVKV FLLPDKKKKF ETKVHRKTLN PVFNEQFTFK VPYSELGGKT LVMAVYDFDR FSKHDIIGEF KVPMNTVDFG HVTEEWRDLQ SAEKEEQEKL GDICFSLRYV PTAGKLTVVI LEAKNLKKMD VGGLSDPYVK IHLMQNGKRL KKKKTTIKKN TLNPYYNESF SFEVPFEQIQ KVQVVVTVLD YDKIGKNDAI GKVFVGYNLE HHHHHH; N- terminal Sequence Analysis: Met-Glu-Pro-Lys-Glu
• Tag: His-tag
• Predicted MW: 29.5 kDa
• Concentration: lot specific
• Purity: >85% pure by SDS-PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified protein; Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 100 mM NaCl
• Preparation: Liquid purified protein
• Protein Description: Recombinant Human SYT1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_001129277
• Locus ID: 6857
• UniProt ID: P21579
• Cytogenetics: 12q21.2
• Synonyms: SYT1, SVP65, SYT, Synaptotagmin1, Synaptotagmin I, SytI, p65
• Summary: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]
• Protein Families: Secreted Protein, Transmembrane