RGS2 (1-211, His-tag) Human Protein
$520.00
3 Weeks*
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Product Data | |
Species | Human |
---|---|
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MQSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T
|
Tag | His-tag |
Predicted MW | 26.5 kDa |
Concentration | lot specific |
Purity | >90% |
Presentation State | Purified |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2 mM DTT, 0.1M NaCl |
Preparation | Liquid purified protein |
Protein Description | Recombinant human RGS2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Reference Data | |
RefSeq | NP_002914 |
Locus ID | 5997 |
UniProt ID | P41220 |
Cytogenetics | 1q31.2 |
Synonyms | G0S8, GIG31 |
Summary | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq, Aug 2009] |
Protein Families | Druggable Genome |
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