ST13 / HIP (1-369) Human Protein
$320.00
3 Weeks*
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Product Data | |
Species | Human |
---|---|
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Protein Sequence
MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRAQK IAEHRRKYER KREEREIKER IERVKKAREE HERAQREEEA RRQSGAQYGS FPGGFPGGMP GNFPGGMPGM GGGMPGMAGM PGLNEILSDP EVLAAMQDPE VMVAFQDVAQ NPANMSKYQS NPKVMNLISK LSAKFGGQA
|
Predicted MW | 41.3 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Presentation State | Purified |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.1 M NaCl, 10% glycerol |
Endotoxin | < 1.0 EU per 1 μg of protein (determined by LAL method) |
Preparation | Liquid purified protein |
Protein Description | Recombinant human Hip was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Reference Data | |
RefSeq | NP_001265518 |
Locus ID | 6767 |
UniProt ID | B4E0U6 |
Cytogenetics | 22q13.2 |
Synonyms | Hsc70-interacting protein, FAM10A1, NY-REN-33, SNC6 |
Summary | The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] |
Protein Families | Druggable Genome |
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