West Nile Virus Pre-M (N-term) Human Protein

SKU AR00156PU-N

West Nile Virus Pre-M Protein (N-term) recombinant protein, 0.1 mg

Product Data

• Species: Human
• Expression Host: E. coli
• Concentration: lot specific
• Purity: 95% pure (SDS-PAGE)
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified protein; Buffer System: 20 mM Phosphate buffer, pH 7.5
• Preparation: Liquid purified protein
• Recommended Dilution: ELISA.; Western blot.; Lateral flow.
• Protein Description: Recombinant West Nile Virus Pre-M Protein, N-terminal. N-terminal part of the Pre-M protein immunodominant region. Contains 6 histidines fusion sequence. Molecular weight approximately 20kDa. Reacts with human West Nile Virus positive serum.
• Storage: Store the protein undiluted at 2-8°C for one month or (in aliquots) at -80°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• Synonyms: pre M protein antibody, West Nile virus antibody, WNVgp1 antibody, Genome polyprotein antibody
• Summary: West Nile Virus is part of the flavivirus family, many of which are capable of causing serious illness in humans. The ssRNA + strand virus is enveloped and spherical with a diameter of 40-50 nm, similar to all flaviviruses.; The virion of this virus is a nucleocapsid covered by a lipoprotein envelope. The envelope contains two proteins: the protein M and glycoprotein E. The nucleocapsid is a complex of protein C and mRNA. In immature particles, there are 60 icosaedrally organized trimeric spikes on the surface. Each spike consists of three heterodimers of envelope protein M precursor (prM) and envelope protein E. Inside cells, viral particles will contain a preM particle and E in a complex that matures through proteolytic cleavage and processing in the Golgi apparatus.; WNV has three different effects on humans, the first is asymptomatic infection; the second is a mild febrile syndrome termed West Nile Fever; the third is a neuroinvasive disease termed West Nile meningitis or encephalitis. In infected individuals the ratio between the three states is roughly 110:30:1. The main route of human infection is through the bite of an infected mosquito.
• Protein Families: ELISA.<br />Western blot.<br />Lateral flow.