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Trypsin-1 / PRSS1 Human Protein

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SKU
BA630
Trypsin-1 / PRSS1 human protein, 0.1 mg
Size:
100 ug
  $845.00
2 Weeks*
Bulk/Customize

Other products for "PRSS1 or NM_002769"

Specifications
Specifications
Product Data
Species Human
Protein Source Pancreas
Concentration lot specific
Purity >95% pure by SDS-PAGE.
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized purified protein.
Bioactivity Biological: Shows no chymotrypsin activity when assayed against N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine-p-nitroanilide.
Specific: >/= 2.5 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one µmole of N-Benzyl-L-arginine-pNA per minute at 25°C in 200 mM Tris-HCl, pH 7.8, 20 mM CaCl2.
Reconstitution Method Restore with 80.8 µl 2mM HCl.
Use product immediately after bringing to neutral pH to avoid auto-degradation.
Preparation Lyophilized purified protein.
Protein Description Human Trypsin
Note Caution: All human source materials have tested non-reactive for HIV1, HIV2, HCV, HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Storage Store lyophilized product at -20°C.
After reconstitution, store at 2-8°C for up to two weeks. Long term, store at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_002760
Locus ID 5644
Cytogenetics 7q34
Synonyms TRP1, TRY1, TRYP1, Trypsin I, Cationic trypsinogen, Beta-trypsin, Serine protease 1
Summary This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Neuroactive ligand-receptor interaction
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Documents
Resources

file-alt Citations

Role of Tmem163 in zinc-regulated insulin storage of MIN6 cells: Functional exploration of an Indian type 2 diabetes GWAS associated gene
Chakraborty, Vellarikkal, Sivasubbu et al
Biochem. Biophys. Res. Commun. (2019) 522 (4), 1022-1029 DOI: 10.1016/j.bbrc.2019.11.117
Cited by 16
AI Summary: OriGene's formalin-fixed paraffin-embedded (FFPE) human pancreas sections were used for confocal microscopy to assess TMEM163 expression in pancreatic tissue in this study.
Snippet: 2.4. Confocal microscopy. Formalin-fixed paraffin-embedded (FFPE) sections of human pancreas (Origene technologies, USA) were deparaffinized, followed by gradual rehydration, antigen retrieval and tissue blocking as per usual protocol
Metabolic Imaging of Pancreatic Ductal Adenocarcinoma Detects Altered Choline Metabolism
Penet, Shah, Bharti et al
Clin. Cancer Res. (2014)
AI Summary: OriGene contributed to this study by providing normal human pancreas protein lysate and the anti-GAPDH antibody (Cat. No. TA315247), which were used as controls and for protein detection in molecular characterization experiments.
Snippet: and sodium fluoride (Sigma). Protein lysate from a normal human pancreas was obtained from OriGene (OriGene, Rockville, MD). Protein concentration was estimated using the ... antibody (1:1000) (Cat. No. TA315247, OriGene). GAPDH (glyceraldehyde 3- ... Cite SaveSaving
WB
Showing 1-2 of 2 papers.
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