Trypsin-1 / PRSS1 Human Protein

SKU BA630

Trypsin-1 / PRSS1 human protein, 0.1 mg

Product Data

• Species: Human
• Protein Source: Pancreas
• Concentration: lot specific
• Purity: >95% pure by SDS-PAGE.
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Lyophilized purified protein.
• Bioactivity: Biological: Shows no chymotrypsin activity when assayed against N-succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine-p-nitroanilide.; Specific: >/= 2.5 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one µmole of N-Benzyl-L-arginine-pNA per minute at 25°C in 200 mM Tris-HCl, pH 7.8, 20 mM CaCl2.
• Reconstitution Method: Restore with 80.8 µl 2mM HCl.; Use product immediately after bringing to neutral pH to avoid auto-degradation.
• Preparation: Lyophilized purified protein.
• Protein Description: Human Trypsin
• Note: Caution: All human source materials have tested non-reactive for HIV1, HIV2, HCV, HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
• Storage: Store lyophilized product at -20°C.; After reconstitution, store at 2-8°C for up to two weeks. Long term, store at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient

Reference Data

• RefSeq: NP_002760
• Locus ID: 5644
• Cytogenetics: 7q34
• Synonyms: TRP1, TRY1, TRYP1, Trypsin I, Cationic trypsinogen, Beta-trypsin, Serine protease 1
• Summary: This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Neuroactive ligand-receptor interaction