Alpha-fetoprotein / AFP Human Protein

SKU BA1024

Alpha-fetoprotein / AFP human protein, 1 mg

Product Data

• Species: Human
• Protein Source: Cell culture
• Concentration: lot specific
• Purity: >95% ≥95% pure by PAGE Electrophoresis and Western blot.
• Presentation State: Aff - Purified
• Buffer: Presentation State: Aff - Purified; State: Liquid (0.2 µm filtered) affinity purified fraction.; Buffer System: 0.1M Tris, 0.2M Sodium Chloride, pH 7.5; Preservative: 0.09% Sodium Azide
• Preparation: Liquid (0.2 µm filtered) affinity purified fraction.
• Protein Description: Human Alpha Fetoprotein (AFP) Antigen Grade.
• Note: Caution: The cell line supernatant tested negative for HIV 1, HIV 2, and HCV antibodies, HIV Ag and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
• Storage: Short term (up to 14 days) store at 2-8°C.; Long term, aliquot and store at -20°C.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_001125
• Locus ID: 174
• Cytogenetics: 4q13.3
• Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
• Summary: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
• Protein Families: Druggable Genome, Secreted Protein