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Alpha-fetoprotein / AFP Human Protein

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SKU
BA1024
Alpha-fetoprotein / AFP human protein, 1 mg
Size:
1 mg
  $1,245.00
2 Weeks*
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Specifications
Specifications
Product Data
Species Human
Protein Source Cell culture
Concentration lot specific
Purity >95% ≥95% pure by PAGE Electrophoresis and Western blot.
Presentation State Aff - Purified
Buffer Presentation State: Aff - Purified
State: Liquid (0.2 µm filtered) affinity purified fraction.
Buffer System: 0.1M Tris, 0.2M Sodium Chloride, pH 7.5
Preservative: 0.09% Sodium Azide
Preparation Liquid (0.2 µm filtered) affinity purified fraction.
Protein Description Human Alpha Fetoprotein (AFP) Antigen Grade.
Note Caution: The cell line supernatant tested negative for HIV 1, HIV 2, and HCV antibodies, HIV Ag and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Storage Short term (up to 14 days) store at 2-8°C.
Long term, aliquot and store at -20°C.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_001125
Locus ID 174
Cytogenetics 4q13.3
Synonyms Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
Summary This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. provided by RefSeq, Oct 2019
Protein Categories Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Documents
Resources

file-alt Citations

Noninvasive prediction of HCC with progenitor phenotype based on gadoxetic acid-enhanced MRI
Chen, Wu, Xia et al
Eur Radiol (2019) 30 (2), 1232-1242 DOI: 10.1007/s00330-019-06414-2
AI Summary: OriGene's anti-EpCAM antibody (TA506627) was used for immunohistochemical staining to identify hepatocellular carcinoma samples with progenitor phenotype, thereby contributing to the study’s analysis of tumor marker expression.
Snippet: … Immunohistochemical staining for CK19 (antibody: ab52625, Abcam) and EpCAM (antibody: TA506627, Origene) was performed;- surgery (N = 2), poor imaging quality mainly due to severe motion artifacts during arterial phase (N = 8), and lesions smaller than 1 cm in diameter (N = 3). Immunohistochemical staining for CK19 (antibody: ab52625, Abcam) and EpCAM (antibody: TA506627, Origene
IHC
Showing 1-1 of 1 papers.
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