JAK1 (NM_002227) Human Mass Spec Standard

CAT#: PH313878

JAK1 MS Standard C13 and N15-labeled recombinant protein (NP_002218)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description JAK1 MS Standard C13 and N15-labeled recombinant protein (NP_002218)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213878
Predicted MW 133.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_002218
RefSeq Size 5053
RefSeq ORF 3462
Synonyms JAK1A; JAK1B; JTK3
Locus ID 3716
Cytogenetics 1p31.3
Summary This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
Protein Pathways
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