OPA1 (NM_130832) Human Mass Spec Standard

CAT#: PH311417

OPA1 MS Standard C13 and N15-labeled recombinant protein (NP_570845)


  View other "OPA1" proteins (13)

USD 3,255.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (2)
Mouse Monoclonal OPA1 Antibody (1E8-1D9)
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Transient overexpression lysate of optic atrophy 1 (autosomal dominant) (OPA1), nuclear gene encoding mitochondrial protein, transcript variant 1
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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211417
Predicted MW 109.4 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_570845
RefSeq Size 6291
RefSeq ORF 2826
Synonyms BERHS; largeG; MGM1; MTDPS14; NPG; NTG
Locus ID 4976
UniProt ID E5KLK0
Cytogenetics 3q29
Summary The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017]

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