Alkaline Phosphatase (ALPP) (NM_001632) Human Mass Spec Standard

CAT#: PH310504

ALPP MS Standard C13 and N15-labeled recombinant protein (NP_001623)


  View other "Alkaline Phosphatase" proteins (4)

USD 3,255.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (2)
Transient overexpression lysate of alkaline phosphatase, placental (Regan isozyme) (ALPP)
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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210504
Predicted MW 58 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001623
RefSeq Size 2883
RefSeq ORF 1605
Synonyms ALP; ALPI; IAP; PALP; PLAP; PLAP-1
Locus ID 250
UniProt ID P05187, B2R7C7
Cytogenetics 2q37.1
Summary The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Aug 2020]
Protein Pathways Folate biosynthesis, Metabolic pathways

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