XRCC1 (NM_006297) Human Mass Spec Standard

CAT#: PH304952

XRCC1 MS Standard C13 and N15-labeled recombinant protein (NP_006288)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description XRCC1 MS Standard C13 and N15-labeled recombinant protein (NP_006288)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204952
Predicted MW 69.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_006288
RefSeq Size 2083
RefSeq ORF 1899
Synonyms RCC; RCC
Locus ID 7515
Cytogenetics 19q13.31
Summary The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
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