Lysyl tRNA synthetase(KARS) (NM_005548) Human Mass Spec Standard

CAT#: PH300311

KARS MS Standard C13 and N15-labeled recombinant protein (NP_005539)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description KARS MS Standard C13 and N15-labeled recombinant protein (NP_005539)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200311
Predicted MW 67.9 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_005539
RefSeq Size 1997
RefSeq ORF 1791
Locus ID 3735
Cytogenetics 16q23.1
Summary Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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