Sfrs5 Mouse Gene Knockout Kit (CRISPR)
Srsf5 - mouse gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN316747G1, Sfrs5 gRNA vector 1 in pCas-Guide vector
KN316747G2, Sfrs5 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||BC082593, NM_001079694, NM_001079695, NM_001347415, NM_001347416, NM_009159, XM_006515630|
|Summary||The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. [provided by RefSeq, Nov 2016].|
|Gene Expression Resources|