DAB2IP Human Gene Knockout Kit (CRISPR)
DAB2IP - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN214413G1, DAB2IP gRNA vector 1 in pCas-Guide vector
KN214413G2, DAB2IP gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_032552, NM_138709, XM_005251719, XM_005251721, XM_005251724, XM_011518264, XM_011518265, XM_011518266, XM_011518267, XM_011518270, XM_011518271, XM_017014298, XM_017014299, XM_017014300|
|Synonyms||AF9Q34; AIP-1; AIP1; DIP1/2|
|Summary||DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).[supplied by OMIM, May 2010]|
|Gene Expression Resources|