CABIN1 Human Gene Knockout Kit (CRISPR)

CAT#: KN211750

CABIN1 - human gene knockout kit via CRISPR

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 HDR-mediated knockout kit validation

USD 1,290.00


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol CABIN1
Locus ID 23523
Kit Components

KN211750G1, CABIN1 gRNA vector 1 in pCas-Guide vector

KN211750G2, CABIN1 gRNA vector 2 in pCas-Guide vector

KN211750-D, donor DNA containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001199281, NM_001201429, NM_012295, XM_005261415, XM_005261416, XM_005261417, XM_005261419, XM_006724179, XM_006724180, XM_006724181, XM_011530026, XM_011530029, XM_011530030, XM_017028680, XM_017028681, XM_017028682, XM_017028683, XM_017028684, XR_001755184, XR_001755185
Synonyms CAIN; KB-318B8.7; PPP3IN
Summary Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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