VPS35 Human Gene Knockout Kit (CRISPR)

CAT#: KN210597LP

VPS35 - human gene knockout kit via CRISPR, HDR mediated

HDR-mediated knockout kit validation

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USD 1,657.00

4 Weeks*

    • 1 kit

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Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol VPS35
Locus ID 55737
Kit Components

KN210597G1, VPS35 gRNA vector 1 in pCas-Guide CRISPR vector

KN210597G2, VPS35 gRNA vector 2 in pCas-Guide CRISPR vector

KN210597LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_018206
UniProt ID Q96QK1
Synonyms MEM3; PARK17
Summary This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.