VPS35 Goat Polyclonal Antibody

CAT#: TA302699

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Goat Polyclonal Antibody against VPS35 / MEM3



USD 465.00


Availability*
In Stock

Size
    • 100 ug


Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution ELISA: 1:128000. WB: 1-3µg/ml. IHC:5µg/ml
Reactivities Human (Expected from sequence similarity: Mouse, Rat, Cow)
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-SPESEGPIYEGLIL, from the C Terminus of the protein sequence according to NP_060676.2.
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 91.5 kDa
Gene Name VPS35 retromer complex component
Background This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms MEM3; PARK17
Note In paraffin embedded Human Testis, shows positive staining in Leydig cells, and cytoplasmic staining (dot-like) of some epithelial cells of the epididymis and of the rete testis. Data obtained with a previous batch.
Reference Data
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