LY108 (SLAMF6) (NM_001184715) Human Tagged ORF Clone Lentiviral Particle

SKU RC229827L4V

Lenti ORF particles, SLAMF6 (mGFP-tagged) - Human SLAM family member 6 (SLAMF6), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: LY108
• Synonyms: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC229827).
• ACCN: NM_001184715
• ORF Size: 846 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001184715.1
• RefSeq ORF: 849 bp
• Locus ID: 114836
• UniProt ID: Q96DU3
• Cytogenetics: 1q23.2-q23.3
• Protein Families: Druggable Genome, Transmembrane
• MW: 32.5 kDa
• Summary: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]