LTBP4 (NM_001042544) Human Tagged ORF Clone Lentiviral Particle

SKU RC224230L4V

Lenti ORF particles, LTBP4 (mGFP-tagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: LTBP4
• Synonyms: ARCL1C; LTBP-4; LTBP4L; LTBP4S
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224230).
• ACCN: NM_001042544
• ORF Size: 4872 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001042544.1, NP_001036009.1
• RefSeq Size: 5163 bp
• RefSeq ORF: 4875 bp
• Locus ID: 8425
• UniProt ID: Q8N2S1
• Cytogenetics: 19q13.2
• Protein Families: Druggable Genome
• MW: 173.3 kDa
• Summary: The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]