Nectin 3 (NECTIN3) (NM_015480) Human Tagged ORF Clone Lentiviral Particle
SKU
RC222962L4V
Lenti ORF particles, PVRL3 (mGFP-tagged) - Human poliovirus receptor-related 3 (PVRL3), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Nectin 3 |
Synonyms | CD113; CDW113; NECTIN-3; PPR3; PRR3; PVRL3; PVRR3 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC222962).
|
ACCN | NM_015480 |
ORF Size | 1647 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_015480.1 |
RefSeq Size | 1650 bp |
RefSeq ORF | 1650 bp |
Locus ID | 25945 |
UniProt ID | Q9NQS3 |
Cytogenetics | 3q13.13 |
Domains | IG, ig |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Adherens junction, Cell adhesion molecules (CAMs) |
MW | 60.8 kDa |
Summary | This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
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