KIR2.3 (KCNJ4) (NM_004981) Human Tagged ORF Clone Lentiviral Particle

SKU RC222272L2V

Lenti ORF particles, KCNJ4 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: KIR2.3
• Synonyms: HIR; HIRK2; HRK1; IRK-3; IRK3; Kir2.3
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222272).
• ACCN: NM_004981
• ORF Size: 1335 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004981.1, NP_004972.1
• RefSeq Size: 1913 bp
• RefSeq ORF: 1338 bp
• Locus ID: 3761
• UniProt ID: P48050
• Cytogenetics: 22q13.1
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• MW: 49.5 kDa
• Summary: Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]