SERCA3 (ATP2A3) (NM_005173) Human Tagged ORF Clone Lentiviral Particle

SKU RC221657L4V

Lenti ORF particles, ATP2A3 (mGFP-tagged)-Human ATPase, Ca++ transporting, ubiquitous (ATP2A3), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SERCA3
• Synonyms: SERCA3
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221657).
• ACCN: NM_005173
• ORF Size: 2997 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005173.3
• RefSeq Size: 4698 bp
• RefSeq ORF: 3000 bp
• Locus ID: 489
• UniProt ID: Q93084
• Cytogenetics: 17p13.2
• Domains: Cation_ATPase_C, Cation_ATPase_N, E1-E2_ATPase, Hydrolase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway
• MW: 109.1 kDa
• Summary: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]