Snf1lk2 (SIK2) (NM_015191) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221327L2V

Lenti ORF particles, SIK2 (mGFP-tagged) - Human salt-inducible kinase 2 (SIK2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Snf1lk2
• Synonyms: LOH11CR1I; QIK; SIK-2; SNF1LK2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_015191
• ORF Size: 2778 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221327).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015191.1
• RefSeq Size: 5694 bp
• RefSeq ORF: 2781 bp
• Locus ID: 23235
• UniProt ID: Q9H0K1
• Cytogenetics: 11q23.1
• Protein Families: Druggable Genome, Protein Kinase
• MW: 103.7 kDa
• Gene Summary: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.[UniProtKB/Swiss-Prot Function]