Cytokeratin 18 (KRT18) (NM_000224) Human Tagged ORF Clone Lentiviral Particle

SKU RC220393L2V

Lenti ORF particles, KRT18 (mGFP-tagged) - Human keratin 18 (KRT18), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Cytokeratin 18
• Synonyms: CK-18; CYK18; K18
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220393).
• ACCN: NM_000224
• ORF Size: 1290 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000224.2
• RefSeq Size: 1485 bp
• RefSeq ORF: 1293 bp
• Locus ID: 3875
• UniProt ID: P05783
• Cytogenetics: 12q13.13
• Domains: filament
• Protein Pathways: Pathogenic Escherichia coli infection
• MW: 47.9 kDa
• Summary: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]