MADCAM1 (NM_130760) Human Tagged ORF Clone Lentiviral Particle
SKU
RC219060L2V
Lenti ORF particles, MADCAM1 (mGFP-tagged) - Human mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | MADCAM1 |
Synonyms | MACAM1 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC219060).
|
ACCN | NM_130760 |
ORF Size | 1146 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_130760.2 |
RefSeq Size | 1546 bp |
RefSeq ORF | 1149 bp |
Locus ID | 8174 |
UniProt ID | Q13477 |
Cytogenetics | 19p13.3 |
Protein Pathways | Cell adhesion molecules (CAMs) |
MW | 38.3 kDa |
Summary | The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008] |
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