SASH1 (NM_015278) Human Tagged ORF Clone Lentiviral Particle

SKU RC218866L4V

Lenti ORF particles, SASH1 (mGFP-tagged) - Human SAM and SH3 domain containing 1 (SASH1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SASH1
• Synonyms: CAPOK; dJ323M4.1; DUH1; SH3D6A
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218866).
• ACCN: NM_015278
• ORF Size: 3741 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_015278.3
• RefSeq Size: 7709 bp
• RefSeq ORF: 3744 bp
• Locus ID: 23328
• UniProt ID: O94885
• Cytogenetics: 6q24.3-q25.1
• Domains: SAM, SH3
• MW: 136.5 kDa
• Summary: This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]