WDR59 (NM_030581) Human Tagged ORF Clone Lentiviral Particle

SKU RC218128L4V

Lenti ORF particles, WDR59 (mGFP-tagged) - Human WD repeat domain 59 (WDR59), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: WDR59
• Synonyms: CDW12; FP977; p90-120
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218128).
• ACCN: NM_030581
• ORF Size: 2922 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_030581.3
• RefSeq Size: 3678 bp
• RefSeq ORF: 2925 bp
• Locus ID: 79726
• UniProt ID: Q6PJI9
• Cytogenetics: 16q23.1
• Domains: RWD, WD40
• MW: 109.6 kDa
• Summary: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).[UniProtKB/Swiss-Prot Function]