Metabotropic Glutamate Receptor 5 (GRM5) (NM_000842) Human Tagged ORF Clone Lentiviral Particle

SKU RC216892L4V

Lenti ORF particles, GRM5 (mGFP-tagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant b, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Metabotropic Glutamate Receptor 5
• Synonyms: GPRC1E; mGlu5; MGLUR5; PPP1R86
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216892).
• ACCN: NM_000842
• ORF Size: 3540 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000842.1, NP_000833.1
• RefSeq Size: 4518 bp
• RefSeq ORF: 3543 bp
• Locus ID: 2915
• UniProt ID: P41594
• Cytogenetics: 11q14.2-q14.3
• Domains: 7tm_3, ANF_receptor
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Gap junction, Huntington's disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction
• MW: 128.87 kDa
• Summary: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]